I read with interest your nicely detailed account of how you repaired the conditions experienced by your young kids with
selenium injections. I know that had to be tremendously rewarding for as you, as well as highly educational for the list
members. Thank you for taking the time to share the experience!

But it worries me a bit that you've singled out selenium as the sole hero of your story (i.e.: ".5 mg selenium injection to
each of the three", and "gave the dams 5 mg selenium" and "plan to call vet as soon as they are open this AM to see
how much more selenium I can give safely") even though in fact you used BoSe. You even went so far as to say that
selenium is the generic name for BoSe! (..."I just find it safer and more accurate to use the generic name for the drug.")
This is a bit misleading to the reader, Jenny.

Selenium, far from being merely a generic name for the drug, is the name identifying one of the two equally important
active ingredients in the product. Vitamin E is the name of the other ingredient. For many years we've been calling this
combo 'selenium-tocopherol'. In the current VPB it is identified as 'selenium-Vitamin E'. For those who are interested in
achieving the same level of success in repairing their own goats that you did with yours, I believe it's vital to let them
know that you didn't do it with just selenium injections as you indicated when recounting the experience, but that in fact
the selenium and Vitamin E work as a team to bring about this rapid improvement in debilitated mammals. And BTW,
that's ALL mammals, not just goats. And, it's used for that purpose in all parts of the country, not just in 'selenium
deficient' areas. Using BoSe as a part of the adjunct therapy, for years now I have been routinely repairing cats and
dogs, and helping other people in all parts of the country to do the same thing for their own animals, achieving the same
level of success on them with it that you talk about in your post. In fact, I myself take a 200mcg tablet of selenium along
with a 1000 unit capsule of Vitamin E daily (my own version of BoSe!), and have done this for many years. And trust me;
one very healthy ol' broad! <grin>

So... No matter what your veterinarian may tell you (and what he says is
frankly merely a 'guesstimate' on his part anyway), BoSe should not be
relegated simply to use in so-called 'selenium deficient' areas! In my
view it should be incorporated into the treatment of debilitated animals
whenever and wherever there is a need for immune system stimulus. This
'selenium deficiency', after all, cannot be readily determined, excepting in individual animals, and through blood testing.
Even using that approach, an accurate selenium level in a living animal is hard to pin down... And frankly, the most
reliable way to measure it is by checking a sample of liver tissue at necropsy. Those maps defining selenium-deficient
areas of the USA that we see occasionally are not absolute... They are generally produced by, say, doctoral candidates,
to  fulfill requirements for their advanced degrees, and I guarantee you  that those Doctorial students are not actually
out there testing soils  in the different areas, but only regurgitating for the most part the  work of previous doctoral
candidates that used that same approach. Thus, there is no actual way for the herd owner, or for the veterinarian, to
positively determine that what those maps indicate has any validity at all.

And that 1mg of selenium combined with 50mg of Vitamin E in the BoSe product is designed essentially to boost the
effectiveness of the Vitamin E in stimulating the immune system, and is not really sufficient to replace selenium in an
actually selenium-deficient mammal. So if I  had a positively ID'd selenium-deficient animal, one that was deficient  
enough to be showing classic symptoms of same, I would certainly be  dosing it with a product that contained more
selenium than BoSe does!

For those who are interested in learning more about the levels of selenium present in the popular selenium/Vitamin E
products on the market today, here is a list of them.

BoSe: 1mg selenium, 50mg Vitamin E, in each ml of the product.
MuSe: 5mg selenium, 50mg Vitamin E, in each ml of the product.
Myosel B: 1mg selenium, 50mg Vitamin E, in each ml of the product.
Myosel E: 2.5mg selenium, 50mg Vitamin E, in each ml of the product.
Myosel M: 5mg selenium, 50mg Vitamin E, in each ml of the product.

BTW: If anyone reading this doesn't have a veterinary source available to provide BoSe for you please contact me,
suereith@msn.com, and I can probably direct you to one.

Below is an article I wrote some time ago explaining just how the BoSe works to stimulate the animal's immune system,
enabling it to help in its own repair from within, while we humans work on it from the outside.  As I've sent this post to the
list previously, for those who are in a  
rush and/or don't want to wade thru the pertinent details again, I'll  sum it up right here as briefly as I can:
BoSe works so well to improve the health of mammals because of the  teamwork involved. In each ml of the product
there is 1mg of Selenium, combined with 50mg of Vitamin E (an already well-known immune system stimulant in its own
right), with the result that the selenium causes
the Vitamin E to work 6 times better than it could by itself, and at the same time the Vitamin E renders the selenium in
the combo non-toxic!

The details backing up that statement are found below... For those that is inclined to seek further input on this... Happy
reading! (smile)  BTW At the very bottom of the article, for those who are interested in reading about it, I have provided
an overview of my own routine approach to treating a sick animal, including the adjunct therapy.

Sue Reith
Carmelita Toggs
Bainbridge Island WA20


----- Original Message -----
From: "Sue Reith" suereith@msn.com
Sent: Monday, May 24, 1999 11:52 AM
Subject: BoSe; Selenium/tocopherol: How/why it works to stimulate the  
system (Dwight Cochran DVM)

A list member asks:

>>Where did you get the info on the reasons behind combining selenium  
Vit E?<<

Sue Reith responds: Here's my article on BoSe and how it works...

BoSe; Selenium/tocopherol: 20
How/why it works to stimulate the immune system20 (including the research done by Dwight Cochran DVM)

The means by which BoSe works is essentially that the presence of that 1  mg of Selenium with the 50 mg of Vitamin E in
each ml of BoSe makes the  Vitamin E work 6 times more efficiently, while the presence of the Vitamin E makes that 1
mg of Selenium in the product  non-toxic. You might want to present this to a vet you have a working relationship with,
and tell him it is important to you to keep your goats’ internal defenses strong. It would be helpful if vets would
realize that the owner has a right to maintain a strong immune system in his/her animals as a management tool.

Vets should not be afraid of BoSe, which I believe is what we are dealing with here, and further I suspect it is simply
because of their own lack of understanding regarding the subject. They hear that Selenium is toxic, and by itself in large
amounts it certainly would be, and as a consequence they fear that by providing a client with BoSe they might be
decreeing the death of the client's animal, which is not good for business. But in fact the issue has nothing to do with
whether or
not the area in which they live is sufficient/deficient in selenium, but rather it is the presence of that 1mg of selenium in
combination with the 50mg of Vitamin E in the injection that is so critical to the strengthening of the animal's immune

The vet meds reference book, called the VPB (Veterinary Pharmaceuticals and Biologicals) does not address the
detrimental effect on livestock of too much available environmental selenium that worries vets so when they are
considering the potential use of BoSe, as it isn't really a relevant issue in discussion of the BoSe product. However, they
do discuss the synergistic effect of selenium in combination with Vitamin E. This synergistic effect may be a basic
concept simply understood and taken for granted by chemists and pharmacologists today, although it appears, from the
reticence of Vets to prescribe BoSe, which may be an unproductive approach... I really don't know why you can't pick up
your average livestock management book and read about it... I guess it is one of those things you soak up with research
and experience along the
way... Who knows?

But what I do know is that a well-known and highly respected Caprine Vet by the name of Dwight Cochran, a teaching
Prof at Purdue University School of Vet Medicine, gave a talk back in 1979 (and probably at other times as well, but I
only have a copy of this one) overviewing the  research done by the AASGP (American Ass'n of Sheep and Goat
Practitioners) (currently  renamed AASRP, after they included Llamas among their interests) on this  subject in which he
stated (and I am only giving you a pertinent paragraph here, as the speech was very long):

To wit:

By Dwight E Cochran DVM

Selenium functions as an essential component of glutathione peroxidase, the enzyme that breaks down peroxides, while
tocopherol appears to function as a secondary line of defense against peroxide damage. In the absence of an adequate
intake of selenium, tocopherol will act to
protect the cell membrane. Tocopherol, however, cannot replace the need for selenium.  
This mechanism is the basis for describing tocopherol as an antioxidant for Vitamin A and necessary polyunsaturated
fatty acids. Selenium
compounds also function in the transport of tocopherol within the body.  Further biochemical interrelationships are
beyond the scope of this discussion, but it should be noted that various researchers have shown that there is a close
relationship in the biomedical activities of
selenium and tocopherol and that there is a definite synergistic effect when the two are used together. Tocopherol
reduces the toxicity of selenium drastically and selenium potentiates the effects of tocopherol as much as six times. .

Sue Reith
Carmelita Toggs
Bainbridge Island WA


My own approach, developed over the past few years through observation of the results with and without the use of
BoSe as adjunct therapy, along with whatever else is being used to restore the animal to good health, is that using BoSe
to stimulate the immune system so that the body of the debilitated animal can help itself while I treat it therapeutically
speeds up the repair time markedly.

My routine approach these days when treating a sick animal is the following:

BoSe inj (at the rate of 1cc/40 lbs SQ) is given once daily for 3 days.
Then it is given once every 2nd day for 3 doses. Then once a week for a month.

However, in an animal that is older, so that his/her own immune system functions less efficiently than it did in earlier
years, and in particular when there is some disease involved for which, in this older animal, there is no known cure, I
have found, much to my astonishment,
that continuing BoSe monthly on a permanent basis after having introduced the initial regimen outlined above results in
markedly increased health and greater expectation of longevity in that animal.

To illustrate by drawing from my own experience:
A couple of years ago I discovered a large tumor about the size of a goose egg on the front leg of my 12 year old male
Australian Shepherd. Biopsy revealed that it was a spindle-cell-sarcoma. The veterinarian immediately suggested
surgery to remove it, but I declined, having
learned from experience that once surgery is performed tumors generally metastasize rapidly. I preferred not to put my
old dog thru that stressful process and opted instead to begin the BoSe regimen I spelled out above. I had hoped that
the stimulation of his immune system in this manner would keep the tumor from enlarging more and/or spreading.
Instead, a month later the
tumor had actually shrunk! It was all but imperceptible when palpating the leg! About 6 months later I tried to skip the
monthly BoSe injection, and after 2 months went by I found it had started to grow again, so I immediately went back to
the month injections, which reduced the tumor once again and kept it under control in an all-but-non-existent state for
the remainder of my dog's life. He passed away at just short of 14 years old, of an unrelated cause.

Sue Reith
Carmelita Toggs
Bainbridge Island WA20